Resveratrol Information

Disclaimer: These Statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease. Nothing written here is medical advice. Every person's situation is unique, and they should consult with their healthcare professional before taking anything.

What is Resveratrol

"Resveratrol (3,5,4′-trihydroxy-trans-stilbene) belongs to polyphenols’ stilbenoids group, possessing two phenol rings linked to each other by an ethylene bridge. This natural polyphenol has been detected in more than 70 plant species, especially in grapes’ skin and seeds, and was found in discrete amounts in red wines and various human foods. It is a phytoalexin that acts against pathogens, including bacteria and fungi. As a natural food ingredient, numerous studies have demonstrated that resveratrol possesses a very high antioxidant potential."[1]

Resveratrol Study On Type 2 Diabetics[2]

  • Human randomized placebo-controlled double-blinded parallel clinical trial.
  • Dosage: 1 gram a day for 45 days.

Overview of results from the treatment group

  • Significantly improved Fasting Glucose
  • Significantly brought down elevated levels of insulin
  • Raised HDL
  • Reduced LDL
  • Brought down HbA1c
  • Significantly brought down HOMA-IR(measures how resistant your cells are to insulin)

Chart comparing placebo group to the control group

Some parameters to help better understand the results

[3]Fasting glucose levels
"This measures your blood sugar after an overnight fast (not eating)."[3]

  • 70-99ml/dL is considered healthy
  • 100-125mg/dL is considered Pre diabetic
  • 126 md/dL is considered diabetic

[3]A1C or HbA1c levels
"The A1C test measures your average blood sugar level over the past 2 or 3 months.''[3]

  • 5.7% or below is considered normal
  • 5.7-6.4% is considered diabetic
  • 6.5% or higher is considered diabetic

[4]Fasting Insulin Levels

  • ideal - around 3 µIU/mL
  • normal - around 5 µIU/mL
  • Diabetic - 6.5 µIU/mL or higher

"Testing for the fasting insulin level in the blood can determine whether an individual is pre-diabetic. A normal fasting insulin level is 5 µIU/mL (micro international unit per milliliter) though ideally, this number should be around 3 µIU/mL. If your fasting insulin level is higher than 5 µIU/mL you’re at an increased risk for diabetes and other various degenerative deceases.  In this situation, you should decrease your sugar consumption, especially fructose (sugar from fruit) which disrupts the cell’s insulin receptor sites. A fasting insulin level of 6.5 µIU/mL or above indicates diabetes.

Prolonged exposure to increased levels of insulin predicts much more than just diabetes. Too much insulin has been linked to an increased risk of cancer, as it aids cell growth and creates free radicals in the bloodstream. It’s also associated with liver damage and impaired vascular function.''[4]

[5]HOMA-IR Levels

"HOMA-IR stands for Homeostatic Model Assessment of Insulin Resistance. The meaningful part of the acronym is “insulin resistance”.''[5]

  • insulin sensitive - Less than 1.0
  • early Insulin resistance - greater than 1.9
  • significant insulin resistance - greater than 2.9

Study Conclusion

"The results of this study clearly demonstrate that resveratrol supplementation in the presence of standard antidiabetic medication has major benefits in T2DM patients, which include a pronounced lowering of blood glucose, HbA1c, insulin levels, and insulin resistance, as well as improvement in HDL levels"[2]

Trans-Resveratrol or Cis-Resveratrol?

"The chemical structure of resveratrol is identified in two isomeric forms, cis- and trans-resveratrol. trans form is dominant in terms of its prevalence and different biological activities are attributed, namely in inducing cellular responses such as cell cycle arrest, differentiation, apoptosis"[6]